Version 5.4
Mus musculus Protein: Prox2
Summary
InnateDB Protein IDBP-260684.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prox2
Protein Name prospero homeobox 2
Synonyms 1700058C01Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000105878
InnateDB Gene IDBG-157762 (Prox2)
Protein Structure
UniProt Annotation
Function Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival. {ECO:0000269PubMed:16470382}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in testis. {ECO:0000269PubMed:16470382}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1920672
InterPro IPR009057 Homeodomain-like
IPR023082 Homeo-prospero domain
PFAM PF05044
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BII1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 73422
UniGene Mm.311944
RefSeq NP_780407
MGI ID
MGI Symbol Prox2
OMIM
CCDS CCDS36495
HPRD
IMGT
EMBL AK051700 BC119330 BC119332
GenPept AAI19331 AAI19333 BAC34725

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca