InnateDB Protein
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IDBP-261314.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cst8
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Protein Name
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cystatin 8 (cystatin-related epididymal spermatogenic)
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Synonyms
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Cres; Cst-rs1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000105573
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InnateDB Gene
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IDBG-209122 (Cst8)
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Protein Structure
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Function |
Performs a specialized role during sperm development and maturation.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
Proximal caput region of the epididymis. Lower expression in the testis. Within the testis it is localized to the elongating spermatids, whereas within the epididymis it is exclusively synthesized by the proximal caput epithelium.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0004869
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cysteine-type endopeptidase inhibitor activity
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Biological Process |
GO:0010951
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negative regulation of endopeptidase activity
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Cellular Component |
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PDB ID |
MGI:107161
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InterPro |
IPR000010
Proteinase inhibitor I25, cystatin
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PFAM |
PF00031
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PRINTS |
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PIRSF |
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SMART |
SM00043
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TIGRFAMs |
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Modification |
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SwissProt |
P32766
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
13012
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UniGene |
Mm.467806
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RefSeq |
XP_006498721
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MGI ID |
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MGI Symbol |
Cst8
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OMIM |
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CCDS |
CCDS16848
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HPRD |
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IMGT |
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EMBL |
AF090691
AF091503
AK018943
AK054409
AK161808
BC049753
S49926
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GenPept |
AAC35390
AAC36316
AAC61754
AAH49753
BAB31489
BAC35768
BAE36585
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