InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc52a3

Summary

InnateDB Protein

IDBP-261496.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc52a3

Protein Name

RIKEN cDNA 2310046K01 gene

Synonyms

2310046K01Rik; RFT2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105485

InnateDB Gene

IDBG-209596 (Slc52a3)

Protein Structure

UniProt Annotation

Function

Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), and to a lesser extent by amiloride (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0032217	riboflavin transporter activity

Biological Process

GO:0007605	sensory perception of sound
GO:0032218	riboflavin transport
GO:0034605	cellular response to heat

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

MGI:1916948

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D6X5

PhosphoSite

PhosphoSite-Q9D6X5

TrEMBL

UniProt Splice Variant

Entrez Gene

69698

UniGene

Mm.258262

RefSeq

MGI ID

MGI Symbol

Slc52a3

OMIM

CCDS

CCDS50749

HPRD

IMGT

EMBL

AK009850 AK029091 AK154970 AK170158 AL845161 BC016127 CH466551

GenPept

AAH16127 BAB26542 BAC26290 BAE32962 BAE41605 CAM17704 CAM17705 EDL05945