Version 5.4
Mus musculus Protein: Nup93
Summary
InnateDB Protein IDBP-262161.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nup93
Protein Name nucleoporin 93
Synonyms 2410008G02Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000105174
InnateDB Gene IDBG-181762 (Nup93)
Protein Structure
UniProt Annotation
Function Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus, nuclear pore complex {ECO:0000250}. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0017056 structural constituent of nuclear pore
Biological Process
GO:0006810 transport
GO:0015031 protein transport
GO:0051028 mRNA transport
GO:0051292 nuclear pore complex assembly
Cellular Component
GO:0005643 nuclear pore
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0034399 nuclear periphery
Protein Structure and Domains
PDB ID MGI:1919055
InterPro IPR007231 Nucleoporin interacting component Nup93/Nic96
PFAM PF04097
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BJ71
PhosphoSite PhosphoSite-Q8BJ71
TrEMBL
UniProt Splice Variant
Entrez Gene 71805
UniGene Mm.422766
RefSeq XP_006531438
MGI ID
MGI Symbol Nup93
OMIM
CCDS CCDS22540
HPRD
IMGT
EMBL AJ505051 AK028864 AK045380 AK129055 AK167105 AK169693 BC023140
GenPept AAH23140 BAC26158 BAC32337 BAC97865 BAE39254 BAE41309 CAD43733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca