Version 5.4
Mus musculus Protein: Fgf18
Summary
InnateDB Protein IDBP-262559.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Fgf18
Protein Name fibroblast growth factor 18
Synonyms D130055P09Rik; FGF-18;
Species Mus musculus
Ensembl Protein ENSMUSP00000104987
InnateDB Gene IDBG-160771 (Fgf18)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005104 fibroblast growth factor receptor binding
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005111 type 2 fibroblast growth factor receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0001503 ossification
GO:0001525 angiogenesis
GO:0001957 intramembranous ossification
GO:0001958 endochondral ossification
GO:0002063 chondrocyte development
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0008284 positive regulation of cell proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0030324 lung development
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032332 positive regulation of chondrocyte differentiation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005576 extracellular region
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID MGI:1277980
InterPro IPR002209 Fibroblast growth factor family
IPR008996 Cytokine, IL-1-like
PFAM
PRINTS PR00263
PIRSF
SMART SM00442
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5SQB3
UniProt Splice Variant
Entrez Gene 14172
UniGene
RefSeq
MGI ID
MGI Symbol Fgf18
OMIM
CCDS
HPRD
IMGT
EMBL AL732390 AL772409
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca