Version 5.4
Mus musculus Protein: Atmin
Summary
InnateDB Protein IDBP-263125.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atmin
Protein Name ATM interactor
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000104727
InnateDB Gene IDBG-194669 (Atmin)
Protein Structure
UniProt Annotation
Function Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM (By similarity). Binds to the DYNLL1 promoter and activates its transcription. {ECO:0000250, ECO:0000269PubMed:22167198}.
Subcellular Localization Nucleus {ECO:0000250UniProtKB:O43313}. Note=Nuclear, in discrete foci during G1 phase. {ECO:0000250UniProtKB:O43313}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
GO:0045502 dynein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2682328
InterPro IPR015880 Zinc finger, C2H2-like
PFAM
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P9S1
PhosphoSite PhosphoSite-Q6P9S1
TrEMBL
UniProt Splice Variant
Entrez Gene 234776
UniGene Mm.259736
RefSeq NP_808368
MGI ID
MGI Symbol Atmin
OMIM
CCDS CCDS22694
HPRD
IMGT
EMBL AC162858 AK087334 AK122281 BC027752 BC060631
GenPept AAH27752 AAH60631 BAC39849 BAC65563

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca