InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kcnj12

Summary

InnateDB Protein

IDBP-263945.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kcnj12

Protein Name

potassium inwardly-rectifying channel, subfamily J, member 12

Synonyms

IRK-2; IRK2; Kir2.2; MB-IRK2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104357

InnateDB Gene

IDBG-182121 (Kcnj12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005242	inward rectifier potassium channel activity

Biological Process

GO:0006813	potassium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0051289	protein homotetramerization
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0031224	intrinsic component of membrane

Protein Structure and Domains

PDB ID

MGI:108495

InterPro

IPR003272 Potassium channel, inwardly rectifying, Kir2.2
IPR013673 Potassium channel, inwardly rectifying, Kir, N-terminal
IPR014756 Immunoglobulin E-set
IPR016449 Potassium channel, inwardly rectifying, Kir

PFAM

PF08466
PF01007

PRINTS

PR01325
PR01320

PIRSF

PIRSF005465

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt