InnateDB Protein
|
IDBP-264549.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Slc43a2
|
Protein Name
|
solute carrier family 43, member 2
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000104071
|
InnateDB Gene
|
IDBG-200164 (Slc43a2)
|
Protein Structure
|
|
Function |
Sodium-, chloride-, and pH-independent, high affinity transport of large neutral amino acids. {ECO:0000269PubMed:15659399}.
|
Subcellular Localization |
Membrane {ECO:0000269PubMed:15659399}; Multi-pass membrane protein {ECO:0000269PubMed:15659399}.
|
Disease Associations |
|
Tissue Specificity |
Expressed in intestine, kidney, brain and adipose tissue, heart and testis. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus. {ECO:0000269PubMed:15659399}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0015179
|
L-amino acid transmembrane transporter activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:2442746
|
InterPro |
IPR011701
Major facilitator superfamily
IPR016196
Major facilitator superfamily domain, general substrate transporter
|
PFAM |
PF07690
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8CGA3
|
PhosphoSite |
PhosphoSite-Q8CGA3
|
TrEMBL |
Q5ND25
|
UniProt Splice Variant |
|
Entrez Gene |
215113
|
UniGene |
Mm.487399
|
RefSeq |
XP_006532882
|
MGI ID |
|
MGI Symbol |
Slc43a2
|
OMIM |
|
CCDS |
CCDS25051
|
HPRD |
|
IMGT |
|
EMBL |
AB120363
AK143773
AK159144
AL591440
AL591496
BC042513
BK005643
|
GenPept |
AAH42513
BAD91090
BAE25533
BAE34852
CAI24094
CAI35390
DAA05677
|
|
|