InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GATAD1

Summary

InnateDB Protein

IDBP-26494.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GATAD1

Protein Name

GATA zinc finger domain containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000287957

InnateDB Gene

IDBG-26492 (GATAD1)

Protein Structure

UniProt Annotation

Function

Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me). {ECO:0000269PubMed:20850016}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:21965549}.

Disease Associations

Cardiomyopathy, dilated 2B (CMD2B) [MIM:614672]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. {ECO:0000269PubMed:21965549}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Tissue Specificity

Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes. {ECO:0000269PubMed:21965549}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding