InnateDB Protein
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IDBP-265028.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Fhl5
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Protein Name
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four and a half LIM domains 5
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Synonyms
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1700027G07Rik; Act;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000103839
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InnateDB Gene
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IDBG-132466 (Fhl5)
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Protein Structure
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Function |
May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation- independent manner (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:10086359}. Note=Nuclei of round and elongated spermatids.
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Disease Associations |
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Tissue Specificity |
Testis-specific, temporal expression is coordinated with CREM. {ECO:0000269PubMed:10086359}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
9 [view]
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:1913192
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InterPro |
IPR001781
Zinc finger, LIM-type
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PFAM |
PF00412
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PRINTS |
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PIRSF |
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SMART |
SM00132
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TIGRFAMs |
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Modification |
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SwissProt |
Q9WTX7
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PhosphoSite |
PhosphoSite-Q9WTX7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
57756
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UniGene |
Mm.87325
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RefSeq |
XP_006538188
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MGI ID |
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MGI Symbol |
Fhl5
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OMIM |
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CCDS |
CCDS18009
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HPRD |
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IMGT |
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EMBL |
AF083394
AK006414
BC048473
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GenPept |
AAD23916
AAH48473
BAB24576
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