Version 5.4
Mus musculus Protein: B4galt1
Summary
InnateDB Protein IDBP-265252.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol B4galt1
Protein Name UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Synonyms B-1,4-GalT; B-1,4-GalT1; b4Gal-T1; beta-1,4-GalT; beta-1,4-GalT1; beta4Gal-T1; GalT; Ggtb; Ggtb2;
Species Mus musculus
Ensembl Protein ENSMUSP00000103731
InnateDB Gene IDBG-136505 (B4galt1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008378 galactosyltransferase activity
Biological Process
GO:0002064 epithelial cell development
GO:0002526 acute inflammatory response
GO:0005989 lactose biosynthetic process
GO:0006012 galactose metabolic process
GO:0006486 protein glycosylation
GO:0007155 cell adhesion
GO:0007339 binding of sperm to zona pellucida
GO:0007341 penetration of zona pellucida
GO:0008285 negative regulation of cell proliferation
GO:0009101 glycoprotein biosynthetic process
GO:0009312 oligosaccharide biosynthetic process
GO:0030198 extracellular matrix organization
GO:0030879 mammary gland development
GO:0042060 wound healing
GO:0042127 regulation of cell proliferation
GO:0043065 positive regulation of apoptotic process
GO:0045136 development of secondary sexual characteristics
GO:0048754 branching morphogenesis of an epithelial tube
GO:0050900 leukocyte migration
GO:0051270 regulation of cellular component movement
GO:0060046 regulation of acrosome reaction
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0060055 angiogenesis involved in wound healing
GO:0060058 positive regulation of apoptotic process involved in mammary gland involution
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009986 cell surface
Protein Structure and Domains
PDB ID MGI:95705
InterPro IPR003859 Beta-1,4-galactosyltransferase
IPR027791 Galactosyltransferase, C-terminal
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF02709
PRINTS PR02050
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6LDL0
UniProt Splice Variant
Entrez Gene 14595
UniGene Mm.15622
RefSeq
MGI ID
MGI Symbol B4galt1
OMIM
CCDS
HPRD
IMGT
EMBL AL833775 BC026824 CH466538 M36289
GenPept AAA37295 AAH26824 EDL05426

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca