InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FABP5

Summary

InnateDB Protein

IDBP-26591.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FABP5

Protein Name

fatty acid binding protein 5 (psoriasis-associated)

Synonyms

E-FABP; EFABP; KFABP; PA-FABP; PAFABP;

Species

Homo sapiens

Ensembl Protein

ENSP00000297258

InnateDB Gene

IDBG-26589 (FABP5)

Protein Structure

UniProt Annotation

Function

High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Keratinocytes; highly expressed in psoriatic skin.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	9 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005504	fatty acid binding
GO:0005515	protein binding
GO:0008289	lipid binding

Biological Process

GO:0006006	glucose metabolic process
GO:0006629	lipid metabolic process
GO:0006656	phosphatidylcholine biosynthetic process
GO:0008544	epidermis development
GO:0009611	response to wounding
GO:0015758	glucose transport