InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sp6

Summary

InnateDB Protein

IDBP-266272.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sp6

Protein Name

trans-acting transcription factor 6

Synonyms

1110025J03Rik; AA591031; AI592962; Epfn; Klf14;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103248

InnateDB Gene

IDBG-210093 (Sp6)

Protein Structure

UniProt Annotation

Function

Promotes cell proliferation. {ECO:0000269PubMed:14551215}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:14551215}.

Disease Associations

Tissue Specificity

Ubiquitous. Preferentially expressed by proliferating epithelial cells of teeth, hair follicles and limbs. {ECO:0000269PubMed:14551215}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0008284	positive regulation of cell proliferation
GO:0042481	regulation of odontogenesis

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1932575

InterPro

IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like

PFAM

PF00096

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9ESX2

PhosphoSite

PhosphoSite-Q9ESX2

TrEMBL

A2A708

UniProt Splice Variant

Entrez Gene

83395

UniGene

Mm.476096

RefSeq

XP_006534594

MGI ID

MGI Symbol

Sp6

OMIM

CCDS

CCDS25309

HPRD

IMGT

EMBL

AJ275988 AM295492 AY338955 BC138818 BC138822 CH466556

GenPept

AAI38819 AAI38823 AAR01258 CAC06698 CAL29644 EDL16061