Version 5.4
Mus musculus Protein: Smarcd2
Summary
InnateDB Protein IDBP-267924.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smarcd2
Protein Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Synonyms AW322457; Baf60b;
Species Mus musculus
Ensembl Protein ENSMUSP00000102456
InnateDB Gene IDBG-267922 (Smarcd2)
Protein Structure
UniProt Annotation
Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0016514 SWI/SNF complex
Protein Structure and Domains
PDB ID MGI:1933621
InterPro IPR003121 SWIB/MDM2 domain
IPR019835 SWIB domain
PFAM PF02201
PRINTS
PIRSF
SMART SM00151
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99JR8
PhosphoSite PhosphoSite-Q99JR8
TrEMBL
UniProt Splice Variant
Entrez Gene 83796
UniGene Mm.21772
RefSeq NP_114084
MGI ID
MGI Symbol Smarcd2
OMIM
CCDS CCDS48957
HPRD
IMGT
EMBL AL604045 BC005732
GenPept AAH05732 CAM23787 CAM23791

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca