InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prkar1a

Summary

InnateDB Protein

IDBP-268262.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Prkar1a

Protein Name

protein kinase, cAMP dependent regulatory, type I, alpha

Synonyms

1300018C22Rik; RIalpha; Tse-1; Tse1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102287

InnateDB Gene

IDBG-213854 (Prkar1a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 75 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	75 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008603	cAMP-dependent protein kinase regulator activity

Biological Process

GO:0001707	mesoderm formation
GO:0006468	protein phosphorylation
GO:0006469	negative regulation of protein kinase activity
GO:0007507	heart development
GO:0008283	cell proliferation
GO:0009887	organ morphogenesis
GO:0045214	sarcomere organization
GO:0060038	cardiac muscle cell proliferation

Cellular Component

GO:0005737	cytoplasm
GO:0031594	neuromuscular junction

Protein Structure and Domains

PDB ID

MGI:104878

InterPro

IPR000595 Cyclic nucleotide-binding domain
IPR003117 Dimerization-anchoring domain of cAMP-dependent protein kinase, regulatory subunit
IPR018490 Cyclic nucleotide-binding-like

PFAM

PF00027
PF02197

PRINTS

PIRSF

SMART

SM00100
SM00394

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite