Version 5.4
Mus musculus Protein: Elavl4
Summary
InnateDB Protein IDBP-268435.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elavl4
Protein Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
Synonyms Elav; Hud; PNEM;
Species Mus musculus
Ensembl Protein ENSMUSP00000102207
InnateDB Gene IDBG-174790 (Elavl4)
Protein Structure
UniProt Annotation
Function May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR. Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in brain and testis. {ECO:0000269PubMed:8535975}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 2 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0017091 AU-rich element binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID MGI:107427
InterPro IPR000504 RNA recognition motif domain
IPR002343 Paraneoplastic encephalomyelitis antigen
IPR006548 Splicing factor ELAV/HuD
PFAM PF00076
PRINTS PR00961
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61701
PhosphoSite PhosphoSite-Q61701
TrEMBL J7H3M8
UniProt Splice Variant
Entrez Gene 15572
UniGene Mm.3970
RefSeq NP_034618
MGI ID
MGI Symbol Elavl4
OMIM
CCDS CCDS18471
HPRD
IMGT
EMBL AF041341 AL627206 AL627425 D31953 JX178292
GenPept AAC40080 AFP87475 BAA06723 CAM19662

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca