InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Stx1b

Summary

InnateDB Protein

IDBP-269121.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stx1b

Protein Name

syntaxin 1B

Synonyms

Stx1b2; Stx1bl; Syn1b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101874

InnateDB Gene

IDBG-210393 (Stx1b)

Protein Structure

UniProt Annotation

Function

Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity). May mediate Ca(2+)- regulation of exocytosis acrosomal reaction in sperm. {ECO:0000250, ECO:0000269PubMed:15774481}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000149	SNARE binding
GO:0005484	SNAP receptor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding

Biological Process

GO:0006836	neurotransmitter transport
GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0017157	regulation of exocytosis