InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Npb

Summary

InnateDB Protein

IDBP-269281.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Npb

Protein Name

neuropeptide B

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101801

InnateDB Gene

IDBG-214853 (Npb)

Protein Structure

UniProt Annotation

Function

Has an effect in food intake, on locomotor activity and has an analgesic effect, (in vivo pharmacological studies). May be involved in the regulation of neuroendocrine system, memory and learning (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Detected in brain; more specifically in paraventricular hypothalamic nucleus, hippocampus and several nuclei in midbrain and brainstem. {ECO:0000269PubMed:12719537}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0005515	protein binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway