InnateDB Protein
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IDBP-269433.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ebf3
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Protein Name
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early B-cell factor 3
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Synonyms
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3110018A08Rik; mKIAA4201; O/E-2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000101724
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InnateDB Gene
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IDBG-211411 (Ebf3)
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Protein Structure
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Function |
Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in adult olfactory epithelium. In embryo, expressed in epithalamus, hypothalamus, throughout the brainstem and near the ventricular zones of mesencephalon, in rostral rhombencephalon, in vomeronasal organ, at high level in developing retina, developing spinal cord, at low level in dorsal root ganglia, trigeminal ganglia, glossopharyngeal nerve ganglia. Not expressed in developing inner eat.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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|
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0007275
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multicellular organismal development
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GO:0045893
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positive regulation of transcription, DNA-templated
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Cellular Component |
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PDB ID |
MGI:894289
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InterPro |
IPR002909
IPT domain
IPR014756
Immunoglobulin E-set
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PFAM |
PF01833
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PRINTS |
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PIRSF |
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SMART |
SM00429
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TIGRFAMs |
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Modification |
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SwissProt |
O08791
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PhosphoSite |
PhosphoSite-O08791
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
13593
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UniGene |
Mm.258708
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RefSeq |
NP_001106886
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MGI ID |
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MGI Symbol |
Ebf3
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OMIM |
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CCDS |
CCDS52422
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HPRD |
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IMGT |
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EMBL |
U82442
U92702
U92704
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GenPept |
AAB58322
AAB58324
AAC64323
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