InnateDB Protein
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IDBP-269485.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dlgap3
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Protein Name
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discs, large (Drosophila) homolog-associated protein 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000101700
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InnateDB Gene
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IDBG-189576 (Dlgap3)
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Protein Structure
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Function |
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:15024750}; Peripheral membrane protein {ECO:0000269PubMed:15024750}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000269PubMed:15024750}. Cell junction, synapse {ECO:0000269PubMed:15024750}. Note=Postsynaptic density of neuronal cells.
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Disease Associations |
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Tissue Specificity |
Highly expressed in central and peripherical nervous system (at protein level). {ECO:0000269PubMed:15024750}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
16 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:3039563
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InterPro |
IPR005026
Guanylate-kinase-associated protein
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PFAM |
PF03359
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6PFD5
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PhosphoSite |
PhosphoSite-Q6PFD5
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TrEMBL |
Q3TY61
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UniProt Splice Variant |
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Entrez Gene |
242667
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UniGene |
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RefSeq |
XP_006503166
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MGI ID |
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MGI Symbol |
Dlgap3
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OMIM |
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CCDS |
CCDS18665
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HPRD |
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IMGT |
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EMBL |
AK158868
AY243848
BC057615
BC058433
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GenPept |
AAH57615
AAH58433
AAO89219
BAE34702
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