Mus musculus Protein: Tnfrsf9
Summary
InnateDB Protein IDBP-270383.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnfrsf9
Protein Name tumor necrosis factor receptor superfamily, member 9
Synonyms 4-1BB; A930040I11Rik; AA408498; AI325004; Cd137; CDw137; ILA; Ly63;
Species Mus musculus
Ensembl Protein ENSMUSP00000101296
InnateDB Gene IDBG-205902 (Tnfrsf9)
Protein Structure
UniProt Annotation
Function Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Expressed on the surface of activated T-cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0019955 cytokine binding
Biological Process
GO:0042127 regulation of cell proliferation
GO:0045087 innate immune response (InnateDB)
GO:0070207 protein homotrimerization
GO:2001180 negative regulation of interleukin-10 secretion
GO:2001183 negative regulation of interleukin-12 secretion
Cellular Component
GO:0005615 extracellular space
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1101059
InterPro IPR001368 TNFR/NGFR cysteine-rich region
IPR020413 Tumour necrosis factor receptor 9
PFAM PF00020
PRINTS PR01924
PIRSF
SMART SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P20334
PhosphoSite PhosphoSite-
TrEMBL Q3U3R1
UniProt Splice Variant
Entrez Gene 21942
UniGene Mm.416252
RefSeq
MGI ID 1D0J
MGI Symbol Tnfrsf9
OMIM
CCDS CCDS18976
HPRD
IMGT
EMBL AK154625 AL607084 AL607143 CH466594 DQ832278 J04492 U02567
GenPept AAA40167 AAA93113 ABI30212 BAE32724 EDL14898 EDL14899 EDL14900