Version 5.4
Homo sapiens Protein: CA3
Summary
InnateDB Protein IDBP-27195.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CA3
Protein Name carbonic anhydrase III, muscle specific
Synonyms CAIII; Car3;
Species Homo sapiens
Ensembl Protein ENSP00000285381
InnateDB Gene IDBG-27193 (CA3)
Protein Structure
UniProt Annotation
Function Reversible hydration of carbon dioxide.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Muscle specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016151 nickel cation binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0006979 response to oxidative stress
GO:0015701 bicarbonate transport
GO:0044281 small molecule metabolic process
GO:0045471 response to ethanol
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001148 Alpha carbonic anhydrase
PFAM PF00194
PRINTS
PIRSF
SMART SM01057
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P07451
PhosphoSite PhosphoSite-P07451
TrEMBL V9HWA3
UniProt Splice Variant
Entrez Gene 761
UniGene Hs.82129
RefSeq NP_005172
HUGO HGNC:1374
OMIM 114750
CCDS CCDS6238
HPRD 00260
IMGT
EMBL AC025800 AC084734 AJ006473 AK096880 AK313254 BC004897 CH471068 EU794596 M29452 M29458
GenPept AAA52293 AAH04897 ACJ13650 BAG36064 BAG53390 CAA07056 EAW87133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca