InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rpn2

Summary

InnateDB Protein

IDBP-274269.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rpn2

Protein Name

ribophorin II

Synonyms

1300012C06Rik; AV261018; Rpn-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112081

InnateDB Gene

IDBG-211228 (Rpn2)

Protein Structure

UniProt Annotation

Function

Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016757	transferase activity, transferring glycosyl groups
GO:0043022	ribosome binding

Biological Process

GO:0006487	protein N-linked glycosylation
GO:0007568	aging
GO:0042493	response to drug

Cellular Component

GO:0000421	autophagic vacuole membrane
GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0008250	oligosaccharyltransferase complex
GO:0016020	membrane
GO:0016021	integral component of membrane