Version 5.4
Mus musculus Protein: Adprm
Summary
InnateDB Protein IDBP-274305.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adprm
Protein Name RIKEN cDNA 2310004I24 gene
Synonyms 2310004I24Rik; MDS006;
Species Mus musculus
Ensembl Protein ENSMUSP00000112064
InnateDB Gene IDBG-187000 (Adprm)
Protein Structure
UniProt Annotation
Function Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP- choline and CDP-ethanolamine, but not other non-reducing ADP- sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047631 ADP-ribose diphosphatase activity
GO:0047734 CDP-glycerol diphosphatase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1913608
InterPro IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like
PFAM PF00149
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99KS6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 66358
UniGene Mm.22511
RefSeq NP_079786
MGI ID
MGI Symbol Adprm
OMIM
CCDS CCDS48820
HPRD
IMGT
EMBL AK009142 AK145941 AL645988 BC004029
GenPept AAH04029 BAB26101 BAE26771 CAI25979

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca