Homo sapiens Protein: ASB18
Summary
InnateDB Protein IDBP-292879.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB18
Protein Name ankyrin repeat and SOCS box containing 18
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386532
InnateDB Gene IDBG-84077 (ASB18)
Protein Structure
UniProt Annotation
Function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001496 SOCS protein, C-terminal
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF07525
PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00253
SM00969
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZVZ8
PhosphoSite PhosphoSite-Q6ZVZ8
TrEMBL
UniProt Splice Variant
Entrez Gene 401036
UniGene Hs.639909
RefSeq NP_997721
HUGO HGNC:19770
OMIM
CCDS CCDS46548
HPRD 16514
IMGT
EMBL AC019068 AC079135 AK123854
GenPept BAC85710