InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STON1

Summary

InnateDB Protein

IDBP-293457.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STON1

Protein Name

stonin 1

Synonyms

SALF; SBLF; STN1; STNB1;

Species

Homo sapiens

Ensembl Protein

ENSP00000384615

InnateDB Gene

IDBG-402496 (STON1)

Protein Structure

UniProt Annotation

Function

May be involved in the endocytic machinery. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:11381094}. Membrane {ECO:0000269PubMed:11381094}. Note=Some fraction is membrane-associated.

Disease Associations

Tissue Specificity

Ubiquitous. {ECO:0000269PubMed:11381094}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0016192	vesicle-mediated transport
GO:0030100	regulation of endocytosis

Cellular Component

GO:0030131

clathrin adaptor complex

Protein Structure and Domains

PDB ID

InterPro

IPR008968 Clathrin adaptor, mu subunit, C-terminal
IPR012320 Stonin homology
IPR017110 Stonin
IPR028565 Mu homology domain

PFAM

PF00928

PRINTS

PIRSF

PIRSF037099

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y6Q2

PhosphoSite

PhosphoSite-Q9Y6Q2

TrEMBL

UniProt Splice Variant

Entrez Gene

11037

UniGene

Hs.732016

RefSeq

NP_001185524

HUGO

HGNC:17003

OMIM

605357

CCDS

CCDS1841

HPRD

16100

IMGT

EMBL

AC073082 AC087816 AC091788 AF026169 AF255310 AK309740 AY026319 BC143520

GenPept

AAD39617 AAI43521 AAK11719 AAK57559