Version 5.4
Homo sapiens Protein: STON1
Summary
InnateDB Protein IDBP-293458.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STON1
Protein Name stonin 1
Synonyms SALF; SBLF; STN1; STNB1;
Species Homo sapiens
Ensembl Protein ENSP00000385273
InnateDB Gene IDBG-402496 (STON1)
Protein Structure
UniProt Annotation
Function May be involved in the endocytic machinery. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:11381094}. Membrane {ECO:0000269PubMed:11381094}. Note=Some fraction is membrane-associated.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:11381094}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0016192 vesicle-mediated transport
GO:0030100 regulation of endocytosis
Cellular Component
GO:0030131 clathrin adaptor complex
Protein Structure and Domains
PDB ID
InterPro IPR008968 Clathrin adaptor, mu subunit, C-terminal
IPR012320 Stonin homology
IPR017110 Stonin
IPR028565 Mu homology domain
PFAM PF00928
PRINTS
PIRSF PIRSF037099
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y6Q2
PhosphoSite PhosphoSite-Q9Y6Q2
TrEMBL
UniProt Splice Variant
Entrez Gene 11037
UniGene Hs.732016
RefSeq NP_006864
HUGO HGNC:17003
OMIM 605357
CCDS CCDS1841
HPRD 16100
IMGT
EMBL AC073082 AC087816 AC091788 AF026169 AF255310 AK309740 AY026319 BC143520
GenPept AAD39617 AAI43521 AAK11719 AAK57559

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca