Version 5.4
Homo sapiens Protein: TTC30B
Summary
InnateDB Protein IDBP-293499.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TTC30B
Protein Name tetratricopeptide repeat domain 30B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386181
InnateDB Gene IDBG-75894 (TTC30B)
Protein Structure
UniProt Annotation
Function Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip. {ECO:0000250}.
Subcellular Localization Cell projection, cilium {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030030 cell projection organization
Cellular Component
GO:0005929 cilium
Protein Structure and Domains
PDB ID
InterPro IPR013026 Tetratricopeptide repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N4P2
PhosphoSite PhosphoSite-Q8N4P2
TrEMBL
UniProt Splice Variant
Entrez Gene 150737
UniGene Hs.447659
RefSeq NP_689730
HUGO HGNC:26425
OMIM
CCDS CCDS42784
HPRD 08706
IMGT
EMBL AC073834 AK055552 BC033795 BX647620 CH471058
GenPept AAH33795 BAB70953 CAH56200 EAX11054

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca