Version 5.4
Homo sapiens Protein: GSTK1
Summary
InnateDB Protein IDBP-293997.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GSTK1
Protein Name glutathione S-transferase kappa 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386944
InnateDB Gene IDBG-45743 (GSTK1)
Protein Structure
UniProt Annotation
Function Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
Subcellular Localization Peroxisome {ECO:0000269PubMed:14742434}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:14742434}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 40 [view]
Protein-Protein 39 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0005102 receptor binding
GO:0015035 protein disulfide oxidoreductase activity
Biological Process
GO:0030855 epithelial cell differentiation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005622 intracellular
GO:0005777 peroxisome
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001853 DSBA-like thioredoxin domain
IPR012336 Thioredoxin-like fold
IPR014440 HCCA isomerase/glutathione S-transferase kappa
PFAM PF01323
PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF PIRSF006386
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y2Q3
PhosphoSite PhosphoSite-Q9Y2Q3
TrEMBL
UniProt Splice Variant
Entrez Gene 373156
UniGene Hs.390667
RefSeq NP_001137152
HUGO HGNC:16906
OMIM 602321
CCDS CCDS47731
HPRD
IMGT
EMBL AC073342 AF068287 AF070657 AF087849 AK289570 AK295592 AK299968 AL136938 AY486465 AY520571 BC001231 BC050715 BC063425 CH471198
GenPept AAD20963 AAF65506 AAH01231 AAH50715 AAH63425 AAP97160 AAS00610 AAS01180 BAF82259 BAG58483 BAG61794 CAB66872 EAW51877

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca