Version 5.4
Homo sapiens Protein: CLEC3B
Summary
InnateDB Protein IDBP-29454.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC3B
Protein Name C-type lectin domain family 3, member B
Synonyms TN; TNA;
Species Homo sapiens
Ensembl Protein ENSP00000296130
InnateDB Gene IDBG-29452 (CLEC3B)
Protein Structure
UniProt Annotation
Function Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Found in plasma.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008201 heparin binding
GO:0030246 carbohydrate binding
GO:0036143 kringle domain binding
Biological Process
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0010756 positive regulation of plasminogen activation
GO:0030282 bone mineralization
GO:0071310 cellular response to organic substance
GO:0071560 cellular response to transforming growth factor beta stimulus
Cellular Component
GO:0001652 granular component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P05452
PhosphoSite PhosphoSite-
TrEMBL E9PHK0
UniProt Splice Variant
Entrez Gene 7123
UniGene
RefSeq NP_003269
HUGO HGNC:11891
OMIM 187520
CCDS CCDS2726
HPRD 01759
IMGT
EMBL AC104165 BC011024 CH471055 CR541981 CR542009 X64559 X70910 X70911 X70912 X98121
GenPept AAH11024 CAA45860 CAA50265 CAA66803 CAG46778 CAG46806 EAW64735 EAW64736

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca