InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNF638

Summary

InnateDB Protein

IDBP-295598.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNF638

Protein Name

zinc finger protein 638

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000386433

InnateDB Gene

IDBG-55926 (ZNF638)

Protein Structure

UniProt Annotation

Function

Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (By similarity). Binds to cytidine clusters in double-stranded DNA. {ECO:0000250, ECO:0000269PubMed:8647861}.

Subcellular Localization

Nucleus speckle {ECO:0000255PROSITE- ProRule:PRU00130, ECO:0000269PubMed:11813260, ECO:0000269PubMed:8647861}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	35 [view]
Protein-Protein	34 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003690	double-stranded DNA binding
GO:0003723	RNA binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding