Homo sapiens Protein: CDH24
Summary
InnateDB Protein IDBP-3028.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDH24
Protein Name cadherin 24, type 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000267383
InnateDB Gene IDBG-3024 (CDH24)
Protein Structure
UniProt Annotation
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion. {ECO:0000269PubMed:12734196}.
Subcellular Localization Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008013 beta-catenin binding
GO:0045294 alpha-catenin binding
GO:0070097 delta-catenin binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0016337 single organismal cell-cell adhesion
GO:0034329 cell junction assembly
GO:0034332 adherens junction organization
GO:0045216 cell-cell junction organization
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR015919 Cadherin-like
PFAM PF01049
PF00028
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86UP0
PhosphoSite PhosphoSite-Q86UP0
TrEMBL Q86TS8
UniProt Splice Variant
Entrez Gene 64403
UniGene Hs.155912
RefSeq
HUGO HGNC:14265
OMIM
CCDS CCDS9585
HPRD 13019
IMGT
EMBL AL137477 AY260900 AY260901 AY358199 BC094810 BX248750 CH471078
GenPept AAH94810 AAP20590 AAP20591 AAQ88566 CAB70758 CAD66557 EAW66190 EAW66192