Version 5.4
Homo sapiens Protein: TSC22D4
Summary
InnateDB Protein IDBP-31314.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSC22D4
Protein Name TSC22 domain family, member 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000300181
InnateDB Gene IDBG-31312 (TSC22D4)
Protein Structure
UniProt Annotation
Function Transcriptional repressor.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 44 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006970 response to osmotic stress
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000580 TSC-22 / Dip / Bun
PFAM PF01166
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y3Q8
PhosphoSite PhosphoSite-Q9Y3Q8
TrEMBL A8MWR6
UniProt Splice Variant
Entrez Gene 81628
UniGene Hs.741210
RefSeq NP_112197
HUGO HGNC:21696
OMIM 611914
CCDS CCDS5695
HPRD 18231
IMGT
EMBL AC092849 AJ133115 AK297702 BC001486 BC001966 BC002972 BC010406 CH236956 CH471091
GenPept AAH01486 AAH01966 AAH02972 AAH10406 BAG60060 CAB43491 EAL23831 EAW76527 EAW76528 EAW76529 EAW76531

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca