InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FARSA

Summary

InnateDB Protein

IDBP-31353.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FARSA

Protein Name

phenylalanyl-tRNA synthetase, alpha subunit

Synonyms

CML33; FARSL; FARSLA; FRSA; PheHA;

Species

Homo sapiens

Ensembl Protein

ENSP00000320309

InnateDB Gene

IDBG-31351 (FARSA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.

Experimentally validated
Total	34 [view]
Protein-Protein	34 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004826	phenylalanine-tRNA ligase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006432	phenylalanyl-tRNA aminoacylation
GO:0010467	gene expression
GO:0043039	tRNA aminoacylation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR002319 Phenylalanyl-tRNA synthetase
IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)
IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
IPR006195 Aminoacyl-tRNA synthetase, class II

PFAM

PF00587
PF01409
PF00152

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y285

PhosphoSite