InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FMNL3

Summary

InnateDB Protein

IDBP-31838.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FMNL3

Protein Name

formin-like 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000335655

InnateDB Gene

IDBG-31836 (FMNL3)

Protein Structure

UniProt Annotation

Function

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. {ECO:0000269PubMed:21834987}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:21834987}. Note=Enriched in lamellipodia.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005488	binding
GO:0005515	protein binding
GO:0017048	Rho GTPase binding
GO:0032794	GTPase activating protein binding

Biological Process

GO:0007010	cytoskeleton organization
GO:0008360	regulation of cell shape
GO:0016043	cellular component organization
GO:0016477	cell migration
GO:0030036	actin cytoskeleton organization