InnateDB Protein
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IDBP-31932.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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POP7
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Protein Name
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processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
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Synonyms
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0610037N12Rik; RPP2; RPP20;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000304353
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InnateDB Gene
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IDBG-31930 (POP7)
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Protein Structure
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Function |
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences.
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Subcellular Localization |
Nucleus, nucleolus {ECO:0000269PubMed:14715275}. Cytoplasm {ECO:0000269PubMed:14715275}. Cytoplasmic granule {ECO:0000269PubMed:14715275}. Note=Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
22
[view]
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Protein-Protein |
19
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
2
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002775
DNA/RNA-binding protein Alba-like
IPR014612
Ribonuclease P/MRP, subunit p20
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PFAM |
PF01918
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PRINTS |
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PIRSF |
PIRSF036572
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O75817
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PhosphoSite |
PhosphoSite-O75817
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TrEMBL |
C9JYM0
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UniProt Splice Variant |
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Entrez Gene |
10248
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UniGene |
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RefSeq |
NP_005828
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HUGO |
HGNC:19949
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OMIM |
606113
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CCDS |
CCDS5704
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HPRD |
09357
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IMGT |
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EMBL |
AC009488
BC001430
CH236956
CH471091
U94316
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GenPept |
AAC24113
AAH01430
EAL23821
EAW76495
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