InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLLP

Summary

InnateDB Protein

IDBP-33152.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLLP

Protein Name

plasmolipin

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000219207

InnateDB Gene

IDBG-33150 (PLLP)

Protein Structure

UniProt Annotation

Function

Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006811	ion transport
GO:0009611	response to wounding
GO:0042552	myelination

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043218	compact myelin
GO:0045121	membrane raft
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR008253 Marvel domain
IPR013295 Myelin and lymphocyte (MAL) protein

PFAM

PF01284

PRINTS

PR01884

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y342

PhosphoSite

PhosphoSite-Q9Y342

TrEMBL

J3QLJ3

UniProt Splice Variant

Entrez Gene

51090

UniGene

Hs.632215

RefSeq

NP_057077

HUGO

HGNC:18553

OMIM

600340

CCDS

CCDS10777

HPRD

11854

IMGT

EMBL

AC009090 AC108081 AF137386 AK313910 BC002760 CH471092

GenPept

AAD33060 AAH02760 BAG36633 EAW82915 EAW82917