InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SCN8A

Summary

InnateDB Protein

IDBP-33573.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCN8A

Protein Name

sodium channel, voltage gated, type VIII, alpha subunit

Synonyms

CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4;

Species

Homo sapiens

Ensembl Protein

ENSP00000347255

InnateDB Gene

IDBG-33569 (SCN8A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005248	voltage-gated sodium channel activity

Biological Process

GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport

Cellular Component

GO:0001518	voltage-gated sodium channel complex
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR005821 Ion transport domain
IPR008054 Voltage gated sodium channel, alpha-8 subunit
IPR010526 Sodium ion transport-associated
IPR024583 Domain of unknown function DUF3451

PFAM

PF00520
PF06512
PF11933

PRINTS

PR01667

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite