Version 5.4
Homo sapiens Protein: EBPL
Summary
InnateDB Protein IDBP-33720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EBPL
Protein Name emopamil binding protein-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367516
InnateDB Gene IDBG-33706 (EBPL)
Protein Structure
UniProt Annotation
Function Does not possess sterol isomerase activity and does not bind sigma ligands. {ECO:0000269PubMed:12760743}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:12760743}; Multi-pass membrane protein {ECO:0000269PubMed:12760743}.
Disease Associations
Tissue Specificity Widely expressed with highest levels in liver, lung and kidney. {ECO:0000269PubMed:12760743}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0047750 cholestenol delta-isomerase activity
Biological Process
GO:0016125 sterol metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007905 Emopamil-binding protein
PFAM PF05241
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BY08
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84650
UniGene
RefSeq
HUGO HGNC:18061
OMIM
CCDS
HPRD 13258
IMGT
EMBL AF243433 AL135901 BC018478 BC092471 CH471075
GenPept AAH18478 AAH92471 AAK28348 CAI40717 CAI40718 CAI40719 CAI40720 CAI40721 EAX08832

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca