InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ILVBL

Summary

InnateDB Protein

IDBP-34235.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ILVBL

Protein Name

ilvB (bacterial acetolactate synthase)-like

Synonyms

209L8; AHAS; ILV2H;

Species

Homo sapiens

Ensembl Protein

ENSP00000263383

InnateDB Gene

IDBG-34233 (ILVBL)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane; Single-pass membrane protein.

Disease Associations

Tissue Specificity

Expressed in all tissues tested, with highest expression in heart, pancreas and placenta. {ECO:0000269PubMed:8954801}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0003674	molecular_function
GO:0003824	catalytic activity
GO:0016740	transferase activity
GO:0030976	thiamine pyrophosphate binding

Biological Process

GO:0008150	biological_process
GO:0008152	metabolic process

Cellular Component

GO:0005575	cellular_component
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding
IPR012000 Thiamine pyrophosphate enzyme, central domain
IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
IPR029035 DHS-like NAD/FAD-binding domain
IPR029061 Thiamin diphosphate-binding fold

PFAM

PF02775
PF00205
PF02776

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A1L0T0

PhosphoSite