InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LDHAL6A

Summary

InnateDB Protein

IDBP-34972.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LDHAL6A

Protein Name

lactate dehydrogenase A-like 6A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000280706

InnateDB Gene

IDBG-34970 (LDHAL6A)

Protein Structure

UniProt Annotation

Function

Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. {ECO:0000269PubMed:18351441}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:18351441}.

Disease Associations

Tissue Specificity

Testis-specific. {ECO:0000269PubMed:18351441}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004459	L-lactate dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006096	glycolytic process
GO:0044262	cellular carbohydrate metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001236 Lactate/malate dehydrogenase, N-terminal
IPR001557 L-lactate/malate dehydrogenase
IPR011304 L-lactate dehydrogenase
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR022383 Lactate/malate dehydrogenase, C-terminal

PFAM

PF00056
PF02866

PRINTS

PR00086

PIRSF

PIRSF000102

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt