Version 5.4
| Homo sapiens Protein: RASL10A | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-3550.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | RASL10A | ||||||||
| Protein Name | RAS-like, family 10, member A | ||||||||
| Synonyms | RRP22; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000216101 | ||||||||
| InnateDB Gene | IDBG-3548 (RASL10A) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Potent inhibitor of cellular proliferation. {ECO:0000269PubMed:15833841}. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Nucleus, nucleolus {ECO:0000269PubMed:15833841}. Note=May cycle in and out of the nucleolus in a GTP-dependent manner. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expression appears to be strictly limited to the central nervous system. {ECO:0000269PubMed:8975699}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001806
Small GTPase superfamily IPR003578 Small GTPase superfamily, Rho type IPR003579 Small GTPase superfamily, Rab type IPR013684 Mitochondrial Rho-like IPR020849 Small GTPase superfamily, Ras type IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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| PFAM |
PF00071
PF08477 |
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| PRINTS |
PR00449
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| PIRSF | |||||||||
| SMART |
SM00174
SM00175 SM00173 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q92737 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | A0A024R1C8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 10633 | ||||||||
| UniGene | Hs.73088 | ||||||||
| RefSeq | NP_006468 | ||||||||
| HUGO | HGNC:16954 | ||||||||
| OMIM | 602220 | ||||||||
| CCDS | CCDS13854 | ||||||||
| HPRD | 03744 | ||||||||
| IMGT | |||||||||
| EMBL | AC002059 BC022473 BC040434 BC050739 BC058077 CH471095 Y07847 | ||||||||
| GenPept | AAH22473 AAH40434 AAH50739 AAH58077 CAA69175 EAW59796 EAW59797 | ||||||||