Version 5.4
Homo sapiens Protein: TMEM38A
Summary
InnateDB Protein IDBP-35792.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM38A
Protein Name transmembrane protein 38A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000187762
InnateDB Gene IDBG-35790 (TMEM38A)
Protein Structure
UniProt Annotation
Function Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). {ECO:0000250}.
Subcellular Localization Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005261 cation channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0015672 monovalent inorganic cation transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0033017 sarcoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR007866 TRIC channel
PFAM PF05197
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H6F2
PhosphoSite PhosphoSite-Q9H6F2
TrEMBL
UniProt Splice Variant
Entrez Gene 79041
UniGene Hs.622156
RefSeq NP_076979
HUGO HGNC:28462
OMIM 611235
CCDS CCDS12349
HPRD 15537
IMGT
EMBL AK025981 AK292764 BC001195 CH471106
GenPept AAH01195 BAB15307 BAF85453 EAW84559

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca