Version 5.4
Homo sapiens Protein: ADTRP
Summary
InnateDB Protein IDBP-362208.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADTRP
Protein Name chromosome 6 open reading frame 105
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000404416
InnateDB Gene IDBG-61681 (ADTRP)
Protein Structure
UniProt Annotation
Function Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro). {ECO:0000269PubMed:21868574}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:21868574}; Multi-pass membrane protein {ECO:0000269PubMed:21868574}. Note=Colocalized with TFPI and CAV1 in lipid rafts.
Disease Associations
Tissue Specificity Expressed in cultured endothelial cells and in placenta. {ECO:0000269PubMed:21868574}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006838 FAR-17a/AIG1-like protein
PFAM PF04750
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96IZ2
PhosphoSite PhosphoSite-Q96IZ2
TrEMBL D6R9A9
UniProt Splice Variant
Entrez Gene 84830
UniGene Hs.624016
RefSeq NP_116133
HUGO HGNC:21214
OMIM 614348
CCDS CCDS4521
HPRD 12836
IMGT
EMBL AK300919 AK313114 AL022724 BC007011 CH471087
GenPept AAH07011 BAG35936 BAG62551 CAB38130 CAI20503 EAW55304 EAW55306

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca