Version 5.4
Homo sapiens Protein: SVIP
Summary
InnateDB Protein IDBP-36261.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SVIP
Protein Name small VCP/p97-interacting protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000346130
InnateDB Gene IDBG-36259 (SVIP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Smooth endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043621 protein self-association
Biological Process
GO:0010508 positive regulation of autophagy
GO:0031333 negative regulation of protein complex assembly
GO:1903061 positive regulation of protein lipidation
GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0000836 Hrd1p ubiquitin ligase complex
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0030868 smooth endoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NHG7
PhosphoSite PhosphoSite-Q8NHG7
TrEMBL
UniProt Splice Variant
Entrez Gene 258010
UniGene Hs.617145
RefSeq NP_683691
HUGO HGNC:25238
OMIM
CCDS CCDS41627
HPRD
IMGT
EMBL AF527534
GenPept AAM88869

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca