Version 5.4
Homo sapiens Protein: GART
Summary
InnateDB Protein IDBP-362981.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GART
Protein Name phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Synonyms AIRS; GARS; GARTF; PAIS; PGFT; PRGS;
Species Homo sapiens
Ensembl Protein ENSP00000413803
InnateDB Gene IDBG-2218 (GART)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004637 phosphoribosylamine-glycine ligase activity
Biological Process
GO:0009113 purine nucleobase biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR016185 Pre-ATP-grasp domain
IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
IPR020562 Phosphoribosylglycinamide synthetase, N-terminal
PFAM PF01071
PF02844
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JZG2
UniProt Splice Variant
Entrez Gene 2618
UniGene Hs.732078
RefSeq
HUGO HGNC:4163
OMIM 138440
CCDS
HPRD 00716
IMGT
EMBL AP000302 AP000303
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca