Version 5.4
Homo sapiens Protein: CLCN7
Summary
InnateDB Protein IDBP-363106.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLCN7
Protein Name chloride channel 7
Synonyms CLC-7; CLC7; OPTA2; OPTB4; PPP1R63;
Species Homo sapiens
Ensembl Protein ENSP00000410907
InnateDB Gene IDBG-8979 (CLCN7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005524 ATP binding
GO:0015297 antiporter activity
Biological Process
GO:0006810 transport
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0044070 regulation of anion transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000644 CBS domain
IPR001807 Chloride channel, voltage gated
IPR002249 Chloride channel ClC-7
IPR014743 Chloride channel, core
PFAM PF00571
PF00654
PRINTS PR00762
PR01118
PIRSF
SMART SM00116
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51798
PhosphoSite PhosphoSite-P51798
TrEMBL Q9BSM4
UniProt Splice Variant
Entrez Gene 1186
UniGene Hs.459649
RefSeq NP_001107803
HUGO HGNC:2025
OMIM 602727
CCDS CCDS45378
HPRD 04103
IMGT
EMBL AF224741 AJ001910 AK056551 AK128285 AK291404 AK292136 AL031600 AL031705 BC004946 BC012737 U88844 Z67743
GenPept AAB48530 AAF34711 AAH04946 AAH12737 BAF84093 BAF84825 BAG51745 BAG54655 CAA05083 CAA91556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca