Version 5.4
Homo sapiens Protein: NEFM
Summary
InnateDB Protein IDBP-364226.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEFM
Protein Name neurofilament, medium polypeptide
Synonyms NEF3; NF-M; NFM;
Species Homo sapiens
Ensembl Protein ENSP00000412295
InnateDB Gene IDBG-12599 (NEFM)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0033693 neurofilament bundle assembly
Cellular Component
GO:0005882 intermediate filament
GO:0030424 axon
GO:0097418 neurofibrillary tangle
Protein Structure and Domains
PDB ID
InterPro IPR001664 Intermediate filament protein
PFAM PF00038
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P07197
PhosphoSite PhosphoSite-P07197
TrEMBL
UniProt Splice Variant
Entrez Gene 4741
UniGene Hs.730072
RefSeq NP_001099011
HUGO HGNC:7734
OMIM 162250
CCDS CCDS47831
HPRD 01205
IMGT
EMBL AF106564 AK294681 BC096757 CH471080 EF560736 Y00067
GenPept AAH96757 ABQ59046 BAG57843 CAA68276 EAW63602

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca