Homo sapiens Protein: ARFIP2
Summary
InnateDB Protein IDBP-364851.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARFIP2
Protein Name ADP-ribosylation factor interacting protein 2
Synonyms POR1;
Species Homo sapiens
Ensembl Protein ENSP00000391427
InnateDB Gene IDBG-29171 (ARFIP2)
Protein Structure
UniProt Annotation
Function Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 27 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019904 protein domain specific binding
GO:0030742 GTP-dependent protein binding
GO:0048365 Rac GTPase binding
Biological Process
GO:0006928 cellular component movement
GO:0007264 small GTPase mediated signal transduction
GO:0030032 lamellipodium assembly
GO:0030036 actin cytoskeleton organization
GO:0031529 ruffle organization
Cellular Component
GO:0001726 ruffle
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005938 cell cortex
Protein Structure and Domains
PDB ID
InterPro IPR010504 Arfaptin homology (AH) domain
PFAM PF06456
PRINTS
PIRSF
SMART SM01015
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P53365
PhosphoSite PhosphoSite-P53365
TrEMBL
UniProt Splice Variant
Entrez Gene 23647
UniGene
RefSeq NP_001229785
HUGO HGNC:17160
OMIM 601638
CCDS CCDS55739
HPRD 07209
IMGT
EMBL AC084337 AK301856 AK304512 BC000392 CH471064 U52522 X97567
GenPept AAA97924 AAH00392 BAG63298 BAG65318 CAA66179 EAW68707 EAW68708