InnateDB Protein
|
IDBP-3651.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
TM9SF1
|
Protein Name
|
transmembrane 9 superfamily member 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000261789
|
InnateDB Gene
|
IDBG-3649 (TM9SF1)
|
Protein Structure
|
|
Function |
Plays an essential role in autophagy. {ECO:0000269PubMed:19029833}.
|
Subcellular Localization |
Lysosome membrane {ECO:0000269PubMed:19029833}; Multi-pass membrane protein {ECO:0000269PubMed:19029833}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269PubMed:19029833}; Multi-pass membrane protein {ECO:0000269PubMed:19029833}.
|
Disease Associations |
|
Tissue Specificity |
Expressed in lung, pancreas, kidney, liver, placenta, skeletal muscle, heart and brain. The amount in skeletal muscle, heart and brain were considerably lower than in the other tissues. {ECO:0000269PubMed:9332367}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
7
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR004240
Nonaspanin (TM9SF)
|
PFAM |
PF02990
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
O15321
|
PhosphoSite |
PhosphoSite-O15321
|
TrEMBL |
G3V1B9
|
UniProt Splice Variant |
|
Entrez Gene |
10548
|
UniGene |
Hs.91586
|
RefSeq |
NP_006396
|
HUGO |
HGNC:11864
|
OMIM |
|
CCDS |
CCDS9617
|
HPRD |
09987
|
IMGT |
|
EMBL |
AL096870
AL136295
BC010856
BX161390
BX161494
CH471078
U94831
|
GenPept |
AAC51782
AAH10856
CAD61879
CAD61941
EAW66073
EAW66075
EAW66076
EAW66077
|
|
|